246 - Tie him to a rock at the seashore and let the waves wear him down to sand over thousands of years.
247 - Spray him with layers and layers of hair spray, then set fire to him.
248 - Fill him with ammonium nitrate fertilizer, dribble diesel fuel on it till saturated. Put a very long fuze on it, light it, and RUN RUN RUN
249 - Raise enough money to give Fred the Box a shot at space tourism. First box on the sun.
250 - Go back in time and kill the man that made Fred the Box. This is called the Connor method. Oh, and you need to destroy his advanced microchip design to keep him from ever being built again.
251 - Lock Fred the Box in a dark room. In the light of a single spotlight sit before him swinging a pocket watch. "You are getting crumbly...."
252 - Lock Fred the Box in the new supercollider at the ESA Physics Lab. For one brief moment, he'll know what it felt like to be a box at the moment of the Big Bang. Which, as far as we know, originally occurred without boxes of any kind.